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Trim37 breast cancer

Web临床诊疗知识库; 中医药知识库; 检索 机构; 作者 WebAug 5, 2024 · Factors affecting response of chemotherapy in women with ovarian cancer. Epithelial ovarian cancer stem cells-a review. Enhanced apoptotic effects of novel paclitaxel analogs on NCI/ADR-RES breast cancer cells. P-glycoprotein in breast cancer; Debate: Treatment of Patients With Recurrent Ovarian Cancer With Antiangiogenic Agents in …

Oncogenic TRIM37 Links Chemoresistance and …

WebAug 2, 2024 · Object . Proliferation and invasion are typical characteristics of breast cancer (BC) cells. Long noncoding RNA NUTM2A-AS1 has been shown to be dysregulated in tumors. This research was to explore the effect of NUTM2A-AS1 on the proliferation and invasion of BC cell lines. Method . Using the tumor database (TCGA) and analysis … WebSep 11, 2024 · 最近,研究人员发现:细胞分裂的“变阻器”TRIM37 ,有望为乳腺癌的细胞中心体靶向治疗做贡献。. 该项研究于9月9日发表在《Nature》上,题为:“Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer”。. 该团队致力于研究的乳腺癌细胞过度表达物质TRIM37 ... chrome is taking too much cpu https://tycorp.net

The TRIM proteins in cancer: from expression to emerging regulatory

WebJan 16, 2024 · Previous studies have demonstrated altered expression levels of TRIM37 in breast and ovarian cancer, which confirmed its oncogenic function (8,9). The present study used RT-qPCR, immunostaining and western blotting to determine that the increased expression of TRIM37 occurred at the transcriptional and post-transcriptional levels in … Web1 day ago · Breast cancer is the world’s most prevalent cancer, and according to the World Health Organization, there were 7.8 million women in 2024 who were diagnosed with breast cancer within the past 5 ... chrome is the worst browser

The TRIM proteins in cancer: from expression to emerging

Category:Breast carcinoma with amplified HER2: a gene expression …

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Trim37 breast cancer

Possible gene for “triple-negative” breast cancer identified

Web12 hours ago · TV presenter Sarah Beeny has been given the all-clear from doctors after being diagnosed with breast cancer. The 51-year-old, best known for appearing on Help! My House Is Falling Down and Sarah ... WebMar 22, 2010 · Discovery study. We previously described a breast cancer TMA assembled from archived tumor samples seen at a regional cancer referral center, the Clearview Cancer Institute of Huntsville (CCIH) that included 69 HER2 expressing cases. As part of a large project aimed at translating the emerging gene expression based classification of …

Trim37 breast cancer

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WebSep 4, 2024 · TRIM37 or PEX5 depletion induces apoptosis and enhances sensitivity to oxidative stress, underscoring the cellular requirement for functional peroxisomes. … Web9 hours ago · First published on Fri 14 Apr 2024 14.33 EDT. Sarah Beeny, the broadcaster and property expert, has announced that she has been given the all-clear after receiving treatment for breast cancer. The ...

Weboncogenic trim37 is a targetable epigenetic driver of metastasis and links chemoresistance and metastatic fate in triple-negative breast cancer [p]. 外国专利: WO2024150770A1 . 2024-07-29 WebTRIM37 elevation in specific cancers. The TRIM37 locus is at the border of 17q22 and 17q23, a chromosomal region amplified in a number of cancers, most prominently …

WebNov 24, 2014 · The TRIM37 (also known as MUL) gene is located in the 17q23 chromosomal region, which is amplified in up to ∼ 40% of breast cancers 1.TRIM37 contains a RING … WebJun 15, 2024 · Previous studies showed that TRIM37 exerted histone H2A ubiquitination and drive centrosome dysfunction of breast cancer [10, 48]. H2A ubiquitinating modification is …

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WebApr 28, 2024 · In addition, tripartite motif-containing protein 37 (TRIM37) has been shown to be involved in the development of breast cancer , but the role of TRIM37 in breast cancer chemotherapy is unclear. The purpose of the present study was to investigate the association between TMPO-AS1 and breast cancer drug resistance, and to identify the … chrome itpWeb9 hours ago · First published on Fri 14 Apr 2024 14.33 EDT. Sarah Beeny, the broadcaster and property expert, has announced that she has been given the all-clear after receiving … chrome is using bingWebIn clinical analyses, we find TRIM37 is upregulated in multiple breast cancer datasets, supporting our findings that the TRIM37-AP-2γ interaction is essential for breast cancer tumor growth. Overall, our work reveals that TRIM37 is an oncogenic coactivator of AP-2γ in breast cancer and provides a novel therapeutic target for treating the disease. chrome is using a lot of memoryWebOncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer Cancer Res . 2024 Nov 1 The majority of clinical deaths in patients with triple-negative breast cancer (TNBC) are due to chemoresistance and aggressive metastases, with high prevalence in younger women of African ethnicity. chrome itunes keyboard issuesWebTripartite motif-containing protein 37 (TRIM37), also known as MUL, contains a RING finger domain, and is identified to be an E3 ubiquitin ligase. 7 TRIM37 is located on the 17q23 chromosome, which is reported to be amplified in up to 40% of breast cancers. 8 As a carcinogenic H2A ubiquitin ligase, TRIM37 is overexpressed in breast cancer and ... chrome is your default browserWeb7 hours ago · The first ever recipient of a new breast cancer vaccine has been revealed to the public. Jennifer Davis, of Ohio, received the breakthrough vaccine, developed by … chrome it polishWebNov 3, 2024 · Although TRIM37 promotes tumorigenesis, its function in breast cancer metastasis and the therapeutic implications of TRIM37 targeting remain to be … chrome it pmb