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Thrap3 gene

WebOct 25, 2024 · Thrap3 colocalizes with R-loops, and Thrap3 depletion leads to R-loop accumulation. Thrap3 is an RNA-binding protein related to the DNA damage response … WebDec 4, 2024 · Thrap3 promotes osteogenesis by inhibiting the degradation of Runx2. Zhou L, Li H, Sun S, Zhang T, Yu Y, Xu L, Wang MZhou L, et al. FASEB J, 2024 Apr. PMID 35230719; Thrap3 promotes R-loop resolution via interaction with methylated DDX5. Kang HJ, Eom HJ, Kim H, Myung K, Kwon HM, Choi JHKang HJ, et al. Exp Mol Med, 2024 Oct. PMID 34697388

THRAP3 Gene - GeneCards TR150 Protein TR150 Antibody

WebTHRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar … WebTHRAP3 depletion increased basal and tumor necrosis factor α (TNFα)-induced lipolysis, proinflammatory gene expression, and phosphorylation of extracellular signal-regulated kinases (ERKs ... growing up right before our eyes https://tycorp.net

THRAP3 and BCLAF1 functionally compensate for each other. (A) THRAP3 …

WebOct 25, 2024 · Thrap3 is associated with XRN2 on R-loops, and XRN2 is a downstream target of Thrap3. a U2OS cell lysates were immunoprecipitated with normal IgG (IgG) or an anti-Thrap3 antibody (Thrap3). Precipitates and cell lysates were subjected to immunoblotting for Thrap3 and XRN2. b U2OS cells were transfected with RNaseH1 overexpression … WebSequence variants and/or copy number variants (deletions/duplications) within the THRAP3 gene will be detected with >99% sensitivity. Variants classified as unknown significance … WebTHRAP3. Addgene Alerts Receive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description thyroid hormone receptor … growing up resources

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Category:THRAP3 mediates resistance to DNA damage and is required

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Thrap3 gene

Anti-THRAP3 Antibodies Invitrogen - Thermo Fisher Scientific

WebMar 21, 2024 · anti-THRAP3P1 antibody (Thyroid Hormone Receptor Associated Protein 3 Pseudogene 1) N-Term. Browse Primary Antibodies and Browse Secondary Antibodies. … WebMar 22, 2013 · The key gene, THRAP3 (thyroid hormone receptor associated protein 3, also known as Thrap150), is a selective coactivator for CLOCK-BMAL1 and promotes CLOCK-BMAL1 binding to target genes [61].

Thrap3 gene

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WebMar 21, 2024 · THAP3 (THAP Domain Containing 3) is a Protein Coding gene. Diseases associated with THAP3 include Brain Malformations With Or Without Urinary Tract … WebThrap3 could play indispensable roles in terminal differentiation of adipocytes by enhancing PPARgamma-mediated gene activation cooperatively with Helz2. Data indicate that …

WebApr 8, 2024 · GSK3A-or THRAP3-knockdown (KD) HCT116 or DLD-1 cell lines were generated using a CRISPR/Cas9 system. There were two gRNAs targeting the human GSK3A gene and two gRNAs targeting the human THRAP3 gene. The HCT116 and DLD-1 cells after knockdown of the target genes were screened by puromycin (ST551, Beyotime). WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions …

WebRNA polymerase II (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. In humans, RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized from POLR2C, POLR2E, and … WebSep 26, 2024 · Thrap3 could play indispensable roles in terminal differentiation of adipocytes by enhancing PPARgamma-mediated gene activation cooperatively with …

WebIn chromatin immunoprecipitation assays, endogenous Helz2 and Thrap3 could be co-recruited, in a ligand-dependent manner, to the PPARγ-response elements in Fabp4/aP2 and Adipoq gene enhancers in differentiated 3T3-L1 cells. These findings collectively suggest that Thrap3 could play indispensable roles in terminal differentiation of adipocytes ...

WebThe most interconnected hub genes detected for the width module encode for proteins implicated in the adaptive responses to oxidative stress (i.e., THRAP3 and PRPF40A ), and a member of the ... filsnown for windowsWebSep 8, 2024 · Thyroid hormone receptor-associated protein 3 (THRAP3) was previously reported to promote diabetic gene expression by acting as a transcriptional coregulator of … fils nylonWebTHRAP3 has 6,565 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 76 datasets. Click the + buttons to view associations for ... growing up roughWebThe most interconnected hub genes detected for the width module encode for proteins implicated in the adaptive responses to oxidative stress (i.e., THRAP3 and PRPF40A ), and a member of the ... growing up roblox songWebDec 2, 2024 · Gene ID: 256643, updated on 29-Mar-2024. Download Datasets Summary. Go to the top of the page Help. Official ... BCLAF1 and THRAP3 family member 3 provided by HGNC Primary source HGNC:HGNC:27413 See related Ensembl:ENSG00000173681 AllianceGenome:HGNC:27413 Gene type protein coding fils oden one pieceWebExpression of THRAP3 (BCLAF2, TRAP150) in cancer tissue. ... THRAP3: Gene description i. Thyroid hormone receptor associated protein 3: Protein class i. Plasma proteins: Predicted location i Intracellular: Number of transcripts i. 3: HUMAN PROTEIN ATLAS INFORMATION i. RNA category i, ... fils nolwennThyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene. filson 10023