WebGas transport and free volume properties of photopolymerized thiol-ene networks for various applications are reported. For basic, commercially-available thiol-ene formulations, oxygen permeation was strictly dependent on the difference between Ttest (room temperature for this work) and network Tg. Networks with Tg near Ttest demonstrated … WebMar 22, 2024 · Tissue oxygen levels are known to be critical to regulation of many cellular processes, including the hepatic metabolism of therapeutic drugs, but its impact is often ignored in in vitro assays. In this study, the material-induced oxygen scavenging property of off-stoichiometric thiol-enes (OSTE) was exploited to create physiologically relevant …
Exploring the advantages of oxygen-tolerant thiol-ene …
Webto produce tailored materials with a 75, 50 and 25% of thiol-ene/thiol-epoxy networks. A photoinitiator was used to trigger the radical thiol-ene polymerization and a latent amine precursor was used to start the base-catalyzed thiol-epoxy click reaction. Neat thiol-ene and thiol-epoxy materials were prepared and taken as the references. WebOn the other hand, thiyl radicals (R-S • ) are the reactive species in the oxidation of thiol moieties by oxygen, as well as in thermal or photo-initiated thiol-ene reactions [58]. ... larissa noel
Tunable Quantum Photoinitiators for Radical Photopolymerization
WebAug 21, 2009 · Oxygen transport characteristics, i.e., permeability, diffusivity, and solubility, have been determined for a variety of photopolymerized thiol−ene networks. Despite the abundance of thiol−ene research and the importance of such information, it is until now … WebFeb 28, 2024 · Through oxidation, reduction, and disulfide exchange, thiol groups play an important role in signaling and homeostasis. Single tubs of tiny molecules (e.g., cysteine), peptides (e.g., glutathione), and thiol proteins (e.g., thioredoxin) that are not in balance and have particular oxidized/reduced ratios, making up the total thiol pool ( 13 ... WebOxygen plays a pivotal role in cellular homeostasis, and its partial pressure determines cellular function and fate. ... To overcome this limitation, we have adapted an off-stoichiometric thiol–ene-epoxy polymer to efficiently remove dissolved oxygen to below 1 hPa and also integrated this modified polymer into a functional biochip material ... larissa newton linkedin