WebJun 8, 2024 · In the Phase Ib/II FORWARD II study (abstract #6004), ImmunoGen’s folate receptor alpha (FRα) targeting antibody-drug conjugate, mirvetuximab soravtansine, in combination with Avastin, generated a 47% overall response rate (ORR) in all of the study cohorts, with a reduction in tumour burden in 92% of the patients. WebFeb 9, 2024 · In the phase 3 FORWARD I trial, Mirv had fewer high grade (≥3) events, dose modifications, and discontinuations compared to standard of care chemotherapy [24]. While a majority of the data ...
Phase III, randomized trial of mirvetuximab soravtansine …
WebMay 19, 2024 · MATURE DATA FROM FORWARD II DOUBLET COHORT WITH BEVACIZUMAB. The cohort enrolled 60 patients with a median age of 60 and a median … WebMar 18, 2024 · Trial courts in Texas used to process more than 10,000 jury trials a year but watched that number plummet to just over 200 in 2024. To address the crunch, court systems had to get creative. cover body theory of phonation
Dr. Monk on the FORWARD I Trial in Ovarian Cancer - OncLive
WebMay 1, 2024 · “These Phase 1 results have played an important role in determining the appropriate dose for mirvetuximab soravtansine in the recently initiated Phase 3 FORWARD I trial of patients with platinum ... WebAug 8, 2013 · This was a multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase 2 trial of Sprifermin administered intra-articularly in participants with primary osteoarthritis of the knee and Kellgren-Lawrence Grade 2 or 3. The trial was intended to investigate the efficacy and safety of different intra articular dosages of ... WebFeb 21, 2024 · ImmunoGen has used a PS2+ rescoring method to assess tumor samples for FRα expression for patients from FORWARD I trial to assess their eligibility for the … cover bonus pathfinder